Yes. HaloMicroscopy can image live, unstained, and unrestrained specimens in hydrated conditions, allowing you to capture both structural detail and dynamic behaviour in real time.

Some examples have included motile cells, small organisms, and tissue cultures— Get in Touch with us if you’d like to discuss your specific application.

HaloMicroscopy can capture structural detail from complex or layered samples in two ways:

• Composite imaging: By combining images from multiple angled illuminations, it builds a single high-contrast HaloImage that reveals surface and internal features based on how the sample scatters light.
• Focal-plane imaging: You can also acquire images at different focus depths to explore features across vertical layers or to create Z-stack-style image sets.

• Adjust exposure time to control brightness.
• Fine-tune gain to enhance faint signals (note: high gain may increase background noise).
• Use the light cover to reduce stray reflections and improve clarity.

For more details, refer to the User Manual in Resources section.

HaloMicroscopy can detect structures well below the diffraction limit, with features as small as 15 nm gold particles successfully visualized. Visibility depends on the material’s optical properties.

Unsure about your sample? Request a Demo or Submit a Sample to test it.

Yes. HaloMicroscopy enables real-time imaging of dynamic changes across various sample types. It’s also compatible with heating stages for observing heat-induced transformations like swelling, drying, or phase changes.

Yes. HaloMicroscopy offers fast, high-resolution, label-free imaging—ideal for assessing surface features, consistency, and defects with minimal prep. It’s a powerful tool for both research and production workflows.

The HaloElement captures up to 15 images from different LED positions. These are automatically combined using a spatial encoding scheme (like positions on a clock face), creating a full-field composite view with enhanced contrast and depth information.

Composite HaloImages can reveal both surface features and internal structure based on differences in geometry and refractive index. The angular information encoded in the image helps distinguish fine details, edges, and orientations—even in complex samples like fibres, flakes, or tissue layers.

A standard composite image is automatically generated by the HaloVision software using 15 sequentially acquired frames. Users also have access to the raw data, enabling custom post-processing in tools like Fiji. 

For more details, refer to the Image Processing Tutorials.

Yes. While the default composite includes all 15 angular frames, users can open individual channels in Fiji and selectively combine, color, or process them based on your needs. 

To know more, refer to the Image Processing Tutorials or Contact Us.

Insert the slide shim and glass podium, attach the plate, connect cables, and place the unit flat on the stage.

See the User Manual for full instructions.

• OS: Windows 10 or 11 Pro
• CPU: Intel® Core™ i9 (13th gen or higher)
• RAM: 16 GB
• Storage: 1 TB (SSD recommended)
• GPU: NVIDIA RTX™ A2000 or equivalent (6 GB VRAM)
• Ports: 1× USB-C, 2× USB-A (SuperSpeed)

Before installation, make sure your system has:

• A camera driver (Spinnaker SDK)
• Python 3.10 or newer (added to PATH)
• CUDA Toolkit (if using GPU acceleration)
• Fiji for image processing

You’ll receive the HaloVision installer link directly from Tiny Bright Things.

The upright microscope and HaloElement should be in a located in low vibration environment, on a counter or benchtop. Optical tables or vibration isolation tables with passive or active vibration dampening may have some benefit to the image performance depending on the background vibration characteristic of the environment.